Butyl iodide → 1-(7-Butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-ethanone

HRID 2180487Notes

Reaction equation

HRID 2180487 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH:14]([CH3:16])[CH3:15])=[CH:7][C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][C:3]=1[C:17](=[O:19])[CH3:18].I[CH2:21][CH2:22][CH2:23][CH3:24]>>[CH2:21]([O:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([CH:14]([CH3:15])[CH3:16])=[CH:7][C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][C:3]=1[C:17](=[O:19])[CH3:18])[CH2:22][CH2:23][CH3:24]

Participants

3

Reactant 2

HCID 10962Butyl iodideHCID 224909177-Hydroxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl-ethanone2×

Product 1

HCID 224909691-(7-Butoxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)-ethanone

Procedure

Following General Procedure A, 1-(7-hydroxy-4-isopropyl-2,2-dimethyl-2H-chromen-6-yl)ethanone (Compound 62, 205 mg, 0.65 mmol) and 1-iodobutane (0.35 mL, 3.24 mmol) were reacted to produce the title compound as a yellow oil.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-aa9968707019401a83ffea5f05510f20
Source dataset
uspto-grants-2005_05
Patent number
US06887896B1

Reaction notes

Loading…