Iodoethane → 1-(7-Ethoxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-ethanone

HRID 2180488Notes

Reaction equation

HRID 2180488 reaction equation
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[CH:7][C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][C:3]=1[C:20](=[O:22])[CH3:21].I[CH2:24][CH3:25]>>[CH2:24]([O:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([C:14]3[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=3)=[CH:7][C:8]([CH3:12])([CH3:13])[O:9]2)=[CH:4][C:3]=1[C:20](=[O:22])[CH3:21])[CH3:25]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 224907651-(7-hydroxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-ethanone2×

Product 1

HCID 224910931-(7-Ethoxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-ethanone

Procedure

Following General Procedure A, 1-(7-hydroxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-ethanone (Compound 61, 992 mg, 3.08 nmol) and 1-iodoethane (1.67 mL, 15.4 mmol) were reacted to produce the title compound as a white solid

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-6486f94a76c14b73b28a31902b075960
Source dataset
uspto-grants-2005_05
Patent number
US06887896B1

Reaction notes

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