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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180495Generated: October 30, 2026

Triethyl 2-fluoro-2-phosphonoacetate → HCID 86597834, compound

https://huagongshe.com/reaction/2180495

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethyl 2-fluoro-2-phosphonoacetateHCID 2734865—
Reactant1-(7-Ethoxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-ethanoneHCID 22491093—
ProductHCID 86597834HCID 86597834—

Reaction Steps

Following General Procedure K, triethyl-2-fluoro-2-phosphonoacetate (0.42 mL, 1.70 mmol) and 1-(7-ethoxy-2,2-dimethyl-4-phenyl-2H-chromen-6-yl)-ethanone (Compound 66, 183 mg, 0.57 mmol) were reacted to give the title compound as a colorless oil after purification by flash chromatography (silica gel, 1:9 ethyl acetate/hexane).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887896B1
Source datasetuspto-grants-2005_05
ORD IDord-c809fb5dde6943cbafb8df1e299c6eed
Source noteuspto-grants-2005_05