Tetrapropylammonium → 1-(8-Chloro-7-isopropoxy-4-isopropyl-2,2-dimethyl-2H-chromene-6-yl)-ethanone

Participants

Role	Name	HCID	Charge
Reactant	Tetrapropylammonium	HCID 9559	—
Reactant	Methyl morpholine oxide	HCID 82029	—
Reactant	1-(8-Chloro-7-isopropoxy-4-isopropyl-2,2-dimethyl-2H-chromene-6-yl)-ethanol	HCID 22491042	—
Product	1-(8-Chloro-7-isopropoxy-4-isopropyl-2,2-dimethyl-2H-chromene-6-yl)-ethanone	HCID 22490893	—

Reaction Steps

Following General Procedure M, 1-(8-chloro-7-isopropoxy-4-isopropyl-2,2-dimethyl-2H-chromene-6-yl)-ethanol (Compound 138, 0.92 g, 2.7 mmol), tetrapropylammonium perrunthenate (TPAP, 0.047 g, 0.14 mmol), and 4-methylmorpholine N-oxide (NMO, 0.47 g, 4.1 mmol) were reacted to give the title compound as a yellow oil.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06887896B1
Source dataset	uspto-grants-2005_05
ORD ID	ord-b84f0357c27d4fcea997df8f3213f887
Source note	uspto-grants-2005_05