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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180551Generated: October 30, 2026

Sodium Hydroxide → HCID 11351381, compound

https://huagongshe.com/reaction/2180551

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 20779605HCID 20779605—
ReactantHCID 87973012HCID 87973012—
ReactantHCID 131724862HCID 131724862—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 11351381HCID 11351381—

Reaction Steps

Following General Procedure G, a solution of ethyl 7L(8-chloro-4-isopropyl-7-ethoxy-2,2-dimethyl-2H-chromen-6-yl)-6-fluoro-3-methyl-octa-2E,4E,6E-trienoate (Compound 166, 874 mg, 1.95 mmol) in ethanol and THF was hydrolyzed with 1M NaOH to give rise to the title compound as a light yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887896B1
Source datasetuspto-grants-2005_05
ORD IDord-fd569fa241e243368abeb94a3bfeed46
Source noteuspto-grants-2005_05