Diisobutylaluminumhydride → HCID 22491046, compound

Participants

Reaction Steps

Following General Procedure G-1, ethyl (2E)-3-(3-ethoxy-8-ethyl-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)-2-fluoro-pent-2-enoate (Compound A-42, 42 mg, 0.11 mmol) in toluene (2 mL) and diisobutylaluminum hydride (1.0 M in hexane, 0.48 mL, 0.48 mmol) were reacted to give the title compound after purification by flash chromatography (silica gel, 2.5% ethyl acetate in hexanes).

Provenance & Evidence