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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2180578Generated: November 2, 2026

Dichloromethane → HCID 22490923, compound

https://huagongshe.com/reaction/2180578

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantMethyl morpholine oxideHCID 82029—
ReactantHCID 22490980HCID 22490980—
CatalystHCID 178419074HCID 178419074—
SolventAcetonitrileHCID 6342—
ProductHCID 22490923HCID 22490923—

Reaction Steps

As described in General Procedure H-1, (2E)-2-fluoro-3-(4,4-dimethyl-6-ethoxy-1-isopropyl-3,4-dihydronaphthalen-7-yl)-2-butenol (Compound A-52, 0.180 g, 0.54 mmol), tetrapropylammonium perruthenate (0.027 g, 0.081 mmol) and 4-methylmorpholine N-oxide (0.158 g, 1.35 mmol) were reacted in acetonitrile (1.5 mL) and dichloromethane (7.5 mL) to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06887896B1
Source datasetuspto-grants-2005_05
ORD IDord-9fae947eb2cc4a7c8ec4591249391a25
Source noteuspto-grants-2005_05