Sodium Hydroxide → HCID 22490777, compound

Participants

Reaction Steps

As described in General Procedure J-1, ethyl (2E,4E,6E)-7-(4 bromo-3-ethoxy-8-isopropyl-5,5-dimethyl-5,6-dihydro-naphthalen-2-yl)-6 fluoro-3-methyl-octa-2,4,6-trienoate (Compound A-158, 860 mg, 1.65 mmol) in ethanol was treated with a solution of 1 N NaOH to produce the title compound after purification by recrystallization from acetonitrile.

Provenance & Evidence