HCID 22484967, compound → HCID 22484950, compound

HRID 2181013Notes

Reaction equation

HRID 2181013 reaction equation
C([NH:5][S:6]([CH2:9][CH2:10][CH2:11][CH2:12][O:13][C:14](=[O:16])[CH3:15])(=[O:8])=[O:7])(C)(C)C>FC(F)(F)C(O)=O>[C:14]([O:13][CH2:12][CH2:11][CH2:10][CH2:9][S:6]([NH2:5])(=[O:7])=[O:8])(=[O:16])[CH3:15]

Participants

3

Reactant 1

HCID 22484967HCID 22484967, compound

Product 1

HCID 22484950HCID 22484950, compoundYield 105.1%

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

N-tert-Butyl-4-acetoxybutanesulfonamide (425 mg) was dissolved in trifluoroacetic acid (4.3 ml), and the mixture was stirred at room temperature for 4 hr and concentrated to dryness under reduced pressure. The residue was purified by silica gel column chromatography (chloroform:methanol=49:1) to give 4-acetoxybutanesulfonamide (347 mg) as a brown oil.

Workup

  1. concentrationconcentrated to dryness under reduced pressure
  2. customThe residue was purified by silica gel column chromatography (chloroform:methanol=49:1)

Sources & evidence

ORD record
ord-2945fcac1ecd4044a6d4fcf4876ecd07
Source dataset
uspto-grants-2005_05
Patent number
US06890934B2

Reaction notes

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