HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydantoin → 2-(2,5-Dioxo-4-imidazolidinyl)-n-{4-[(2-methyl-4-quinolinyl)methoxy]phenyl}propanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydantoin | HCID 10006 | — |
| Reactant | 4-[(2-Methyl-4-quinolinyl)methoxy]benzenamine dihydrochloride | HCID 67305537 | — |
| Product | 2-(2,5-Dioxo-4-imidazolidinyl)-n-{4-[(2-methyl-4-quinolinyl)methoxy]phenyl}propanamide | HCID 10180282 | 13% |
Reaction Steps
2-(4-hydantoinyl)propionic acid (50 mg, 0.30 mmol) and 4-[(2-methyl-4-quinolinyl)methoxy]-aniline bis-HCl salt (101 mg, 0.30 mmol) were coupled using general coupling method A to give 20 mg (13%) of the product hydantoin. MS found: (M+H)+=419.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06890915B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-2082ea83014d4d678b03713da86d7201 |
| Source note | uspto-grants-2005_05 |