6-methylpyridine-2-sulfonamide → HCID 76169160, compound

Participants

Role	Name	HCID	Charge
Reactant	6-methylpyridine-2-sulfonamide	HCID 819442	—
Reactant	2-(2,2-Dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-N-(4-fluoro-benzyl)-N-methoxy-acetamide	HCID 73033233	—
Product	HCID 76169160	HCID 76169160	—

Reaction Steps

2-(2,2-Dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-N-(4-fluoro-benzyl)-N-methoxy-acetamide was treated with 6-methyl-pyridine-2-sulfonic acid amide as described in the preparation of compound 1 to yield the title compound. 1H NMR (500 MHz, CDCl3) δ: 2.45 (s, 3), 3.61 (s, 3), 4.73 (s, 2), 6.38 (s, 1), 6.97 (m, 2), 7.23 (m, 2), 7.77 (m, 1), 8.17 (m, 1), 8.54 (s, 1). 13C NMR (125 MHz, CDCl3) δ: 18.71, 48.22, 63.10, 92.48, 115.65, 115.82, 124.67, 130.24, 130.34, 131.09, 138.70, 139.36, 150.54, 152.19, 159.14, 161.66, 163.62, 170.80.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06890942B2
Source dataset	uspto-grants-2005_05
ORD ID	ord-dcafdfdb349640d0bdb3ae03ce46da85
Source note	uspto-grants-2005_05