5-Chlorothiophene-2-Sulfonamide → HCID 72613072, compound

Participants

Role	Name	HCID	Charge
Reactant	5-Chlorothiophene-2-Sulfonamide	HCID 1241301	—
Reactant	2-(2,2-Dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-N-(4-fluoro-benzyl)-N-methoxy-acetamide	HCID 73033233	—
Product	HCID 72613072	HCID 72613072	—

Reaction Steps

2-(2,2-Dimethyl-5-oxo-[1,3]dioxolan-4-ylidene)-N-(4-fluoro-benzyl)-N-methoxy-acetamide was treated with 5-chloro-thiophene-2-sulfonic acid amide as described in the preparation of compound 1 to yield the title compound. 1H NMR (500 MHz, CDCl3) δ: 3.66 (s, 3), 4.77 (s, 2), 6.49 (s, 1), 7.00 (overlapping m, 3), 7.26 (m, 2), 7.72 (m, 1). 13C NMR (125 MHz, CDCl3) δ: 48.29, 63.20, 92.61, 115.69, 115.87, 126.94, 130.23, 130.30, 131.01, 135.19, 135.85, 140.50, 159.01, 159.08, 161.69, 163.66, 170.84.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06890942B2
Source dataset	uspto-grants-2005_05
ORD ID	ord-9d2c043e67f14c90a8d97410dee35e17
Source note	uspto-grants-2005_05