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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181211Generated: November 2, 2026

4-(Chloromethyl)-2-(4-fluorophenyl)-5-methyl-1,3-oxazole → HCID 10432356, compound

https://huagongshe.com/reaction/2181211

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-2-(4-fluorophenyl)-5-methyl-1,3-oxazoleHCID 10609255—
ReactantRac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl esterHCID 69563293—
ProductHCID 10432356HCID 1043235639%

Reaction Steps

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-(4-fluoro-phenyl)-5-methyl-oxazole, the title compound was obtained in 39% yield as a colourless solid. MS: (M+H)30 423.3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-d7bee7d3a8944a9896d4b33605eb829a
Source noteuspto-grants-2005_05