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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181215Generated: October 25, 2026

Oxazole, 4-(chloromethyl)-2-(3,5-dimethoxyphenyl)-5-methyl- → HCID 10412116, compound

https://huagongshe.com/reaction/2181215

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxazole, 4-(chloromethyl)-2-(3,5-dimethoxyphenyl)-5-methyl-HCID 21974252—
ReactantRac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl esterHCID 69563293—
ProductHCID 10412116HCID 1041211650%

Reaction Steps

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-(3,5-dimethoxy-phenyl)-5-methyl-oxazole, the title compound was obtained in 50% yield as a colourless solid. MS: (M−H)− 463.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-275d1989e5bd416e8bd583fd034e4256
Source noteuspto-grants-2005_05