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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181223Generated: November 1, 2026

4-(Chloromethyl)-2-phenyl-1,3-oxazole → HCID 10045901, compound

https://huagongshe.com/reaction/2181223

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-2-phenyl-1,3-oxazoleHCID 3551196—
ReactantRac-2-ethoxy-3-(1h-indol-5-yl)-propionic acid ethyl esterHCID 69563293—
ProductHCID 10045901HCID 1004590180%

Reaction Steps

Starting from rac-2-ethoxy-3-(1H-indol-5-yl)-propionic acid ethyl ester and 4-chloromethyl-2-phenyl-oxazole, the title compound was obtained in 80% yield as a brown oil. MS: (M+H)+ 391.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-3c42431283ba48db81fb805ccd3b120d
Source noteuspto-grants-2005_05