HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Trifluoromethylphenyl)-4-chloromethyl-5-methyloxazole → 2-Propoxypropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Trifluoromethylphenyl)-4-chloromethyl-5-methyloxazole | HCID 10236333 | — |
| Reactant | Methyl α-propoxy-1H-indole-5-propanoate | HCID 69562937 | — |
| Product | 2-Propoxypropanoic acid | HCID 14495546 | — |
Reaction Steps
In analogy to the procedure described in example 44, rac-3-(1H-indol-5-yl)-2-propoxy-propionic acid methyl ester (preparation 6) was reacted with 4-chloromethyl-5-methyl-2-(4-trifluoromethyl-phenyl)-oxazole to give rac-3-1-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl methyl]-1H-indol-5-yl}-2-propoxy-propionic acid as light yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06890947B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-69050f0f31ab4c25a386ef72b9b664a6 |
| Source note | uspto-grants-2005_05 |