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HRID2181243

反应详情

EQUATION

反应方程式

HRID 2181243 的结构方程式

REACTANTS

反应物

2
结构：Cc1cc(-c2nc(CCl)c(C)o2)ccc1F
HCID21974259

4-(Chloromethyl)-2-(4-fluoro-3-methylphenyl)-5-methyloxazole

C12H11ClFNO

结构：COC(=O)C(Cc1ccc2[nH]ccc2c1)Oc1ccccc1
HCID69563280

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(-c2nc(Cn3ccc4cc(CC(Oc5ccccc5)C(=O)O)ccc43)c(C)o2)ccc1F
HCID9982786

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 44, rac-3-(1H-indol-5-yl)-2-phenoxy-propionic acid methyl ester (preparation 7) was reacted with 4-chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazole to give rac-3-{1-[2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazol-4-ylmethyl]-1H-indol-5-yl}-2-phenoxy-propionic acid off-white solid.