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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181243Generated: November 1, 2026

4-Chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazole → HCID 9982786, compound

https://huagongshe.com/reaction/2181243

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazoleHCID 21974259—
ReactantRac-3-(1h-indol-5-yl)-2-phenoxy-propionic acid methyl esterHCID 69563280—
ProductHCID 9982786HCID 9982786—

Reaction Steps

In analogy to the procedure described in example 44, rac-3-(1H-indol-5-yl)-2-phenoxy-propionic acid methyl ester (preparation 7) was reacted with 4-chloromethyl-2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazole to give rac-3-{1-[2-(4-fluoro-3-methyl-phenyl)-5-methyl-oxazol-4-ylmethyl]-1H-indol-5-yl}-2-phenoxy-propionic acid off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-abb8ebab163e48cb83c1d2089ad60746
Source noteuspto-grants-2005_05