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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181256Generated: October 25, 2026

4-(Chloromethyl)-2-(2-chlorophenyl)-5-methyloxazole → HCID 11744618, compound

https://huagongshe.com/reaction/2181256

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-2-(2-chlorophenyl)-5-methyloxazoleHCID 21974256—
ReactantRac-2-ethoxy-3-(4-methyl-1h-indol-5-yl)-propionic acid ethyl esterHCID 69563695—
ProductHCID 11744618HCID 11744618—

Reaction Steps

In analogy to the procedure described in example 44, rac-2-ethoxy-3-(4-methyl-1H-indol-5-yl)-propionic acid ethyl ester [preparation 10h)] was reacted with 4-chloromethyl-2-(2-chloro-phenyl)-5-methyl-oxazole to give rac-3-{1-[2-(2-chloro-phenyl)-5-methyl-oxazol-4-ylmethyl]-4-methyl-1H-indol-5-yl}-2-ethoxy-propionic acid as yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-fd5665782c0e4fe2859a8b6e17499435
Source noteuspto-grants-2005_05