Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2181257Generated: October 26, 2026

Oxazole, 4-(chloromethyl)-2-(3,5-dimethoxyphenyl)-5-methyl- → HCID 11754816, compound

https://huagongshe.com/reaction/2181257

Reaction equation

Participants

RoleNameHCIDCharge
ReactantOxazole, 4-(chloromethyl)-2-(3,5-dimethoxyphenyl)-5-methyl-HCID 21974252—
ReactantRac-2-ethoxy-3-(4-methyl-1h-indol-5-yl)-propionic acid ethyl esterHCID 69563695—
ProductHCID 11754816HCID 11754816—

Reaction Steps

In analogy to the procedure described in example 44, rac-2-ethoxy-3-(4-methyl-1H-indol-5-yl)-propionic acid ethyl ester [preparation 10h)] was reacted with 4-chloromethyl-2-(3,5-dimethoxy-phenyl)-5-methyl-oxazole to give rac-3-{1-[2-(3,5-dimethoxy-phenyl)-5-methyl-oxazol-4-ylmethyl]-4-methyl-1H-indol-5-yl}-2-ethoxy-propionic acid as yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06890947B2
Source datasetuspto-grants-2005_05
ORD IDord-1070fe392b704f74b7c1d1fc1dcfdf23
Source noteuspto-grants-2005_05