HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodo-3,5-dimethoxy-4-(2,2,2-trifluoroethoxy)benzene → 3,5-Dimethoxy-4-(2,2,2-trifluoroethoxy)phenylboronic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodo-3,5-dimethoxy-4-(2,2,2-trifluoroethoxy)benzene | HCID 22485503 | — |
| Reactant | (4-Ethoxy-3,5-dimethoxyphenyl)boronic acid | HCID 22485535 | — |
| Reactant | 4-Ethoxy-1-iodo-3,5-dimethoxybenzene | HCID 22485559 | — |
| Product | 3,5-Dimethoxy-4-(2,2,2-trifluoroethoxy)phenylboronic acid | HCID 22485554 | — |
Reaction Steps
Applying the synthetic procedure of 4-ethoxy-3,5-dimethoxyphenylboronic acid from 4-ethoxy-1-iodo-3,5-dimethoxybenzene in Reference Example 3, the title compound was prepared as a colorless amorphous powder (369.0 mg, yield: 48%) from 1-iodo-3,5-dimethoxy-4-(2,2,2-trifluoroethoxy)-benzene (1.00 g, 2.76 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06890940B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-96250e428b2b42cb9d0d8e29b45cd7a6 |
| Source note | uspto-grants-2005_05 |