HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivaloyl chloride → N-(4-Bromo-2,5-xylyl)pivalamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | 4-Bromo-2,5-dimethylaniline | HCID 8167130 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | N-(4-Bromo-2,5-xylyl)pivalamide | HCID 22481232 | — |
Reaction Steps
To a solution of 4-bromo-2,5-xylidine (8 g) in pyridine (60 ml) was added pivaloyl chloride (4.7 ml) at room temperature. After 30 minutes, the mixture was poured into dilute hydrochloric acid/ice solution. The precipitate was filtered and washed with water to give the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06893650B1 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-7ad043cfbbac4eb9b74863ae9bf65b7b |
| Source note | uspto-grants-2005_05 |