Potassium Carbonate → 3-Fluoro-5-[(3-methoxyphenyl)sulfonyl]-6-methyl-5,6-dihydrophenanthridine

Participants

Reaction Steps

The title compound was prepared from N-[1-(2′,4′-difluoro-1,1′-biphenyl-2-yl)ethyl]-3-methoxybenzenesulfonamide (454 mg, 1.12 mmol), anhydrous N,N-dimethylformamide (2 mL), and potassium carbonate (311 mg, 2.25 mmol) according to the procedure and in the same manner as described in Example 105, step d, and the product (426 mg, 99%) isolated as a white solid, m.p. 115-117° C.;

Provenance & Evidence