Perfluoropropionyl fluoride → HCID 131724885, compound

HRID 2182022Notes

Reaction equation

HRID 2182022 reaction equation
[OH:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH:8]([CH2:10][OH:11])[CH3:9].[C:12]([C:16]([C:19](F)=[O:20])([F:18])[F:17])([F:15])([F:14])[F:13].[C:22]([O-:25])(O)=O.[Na+]>C(Cl)(Cl)Cl>[C:12]([C:16]([C:22]([O:1][CH2:2][CH2:3][O:4][CH2:5][CH2:6][O:7][CH:8]([CH2:10][O:11][C:19]([C:16]([C:12]([F:13])([F:14])[F:15])([F:17])[F:18])=[O:20])[CH3:9])=[O:25])([F:18])[F:17])([F:15])([F:14])[F:13]

Participants

5

Reactant 3

HCID 67912Perfluoropropionyl fluorideHCID 516892Sodium BicarbonateHCID 85633220HCID 85633220, compound

Product 1

HCID 131724885HCID 131724885, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Conditions

Temperature
30 °C

Procedure

HO(CH2)2O(CH2)2OCH(CH3)CH2OH (5.1 g) obtained in Example 5-2 and chloroform (10 g) were charged into a flask and stirred while maintaining the internal temperature at 30° C. Together with nitrogen, CF3CF2COF (191 g) was supplied while maintaining the internal temperature at 30° C. After completion of the reaction, while supplying nitrogen gas, stirring was continued at an internal temperature of 30° C. for 2 hours, and then, a 5% NaHCO3 aqueous solution (30 ml) was added at an internal temperature of at most 15° C.

Workup

  1. temperaturewhile maintaining the internal temperature at 30° C
  2. customAfter completion of the reaction
  3. stirringstirring

Sources & evidence

ORD record
ord-d21a8fbec0d4451eb21bd7fa76546dab
Source dataset
uspto-grants-2005_05
Patent number
US06894187B2

Reaction notes

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