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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218226Generated: October 27, 2026

Ethyl 2-(4-bromophenyl)-2-methylpropanoate → 2-Methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)phenyl)propanoic acid

https://huagongshe.com/reaction/218226

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-(4-bromophenyl)-2-methylpropanoateHCID 11277257—
ReactantEthyl 2-methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)phenyl)propanoateHCID 21099802—
Product2-Methyl-2-(4-(5-(trifluoromethyl)pyridin-2-yl)phenyl)propanoic acidHCID 21099716—

Reaction Steps

The title compound was prepared according to the method of Example 22B, substituting the product of Example 26B for the product of Example 22A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198331B2
Source datasetuspto-grants-2012_06
ORD IDord-2aef6b1798724533bf088b2ab16de01a
Source noteuspto-grants-2012_06