Sodium Chloride → HCID 178499521, compound

HRID 2182384Notes

Reaction equation

HRID 2182384 reaction equation
[CH3:1][O:2][CH:3]([O:8][CH3:9])[C:4](=O)[CH:5]=[CH2:6].O.[NH2:11][NH2:12].[Cl-].[Na+]>O>[CH3:1][O:2][CH:3]([O:8][CH3:9])[C:4]1[CH:5]=[CH:6][NH:12][N:11]=1

Participants

5

Reactant 3

HCID 5234Sodium ChlorideHCID 24654Hydrazine hydrate (1:1)HCID 224778181,1-Dimethoxybut-3-en-2-one

Product 1

HCID 178499521HCID 178499521, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A stirred solution of 1,1-dimethoxy-but-3-en-2-one in water (300 mL) was treated dropwise with hydrazine hydrate (21 ml). After standing at room temperature overnight the reaction mixture was treated with sodium chloride (108 g) and the mixture was then extracted with methyl-t-butylether (200 mL then 100 mL). The combined extracts were dried with magnesium sulfate and then evaporated to give 1H-pyrazol-3-carbaldehyde dimethyl acetal as a light brown oil (18.47 g).

Workup

  1. extractionthe mixture was then extracted with methyl-t-butylether (200 mL
  2. dry with materialThe combined extracts were dried with magnesium sulfate
  3. customevaporated

Sources & evidence

ORD record
ord-3653ee047e614f95a24cd84bc19f53dd
Source dataset
uspto-grants-2005_05
Patent number
US06897208B2

Reaction notes

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