反应详情

To a solution of (5R,7S)-5-(4-Bromobenzyl)-3-(3,5-dichlorophenyl)-7-amino-1,3-diazabicyclo[3.3.0]octane-2,4-dione (0.103 g) in THF (4 mL) was added acetic anhydride (0.031 mL). After 5 hours, the reaction mixture was concentrated and purified by chromatography (silica gel: CH2Cl2, Chromatotron) to afford the titled compound (0.125 g). MS (m/z) 510 (MH+). mp 140.7° C.

1. concentrationthe reaction mixture was concentrated
2. custompurified by chromatography (silica gel: CH2Cl2, Chromatotron)