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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2183459생성일: 2026년 10월 25일

Hydrochloric Acid → (S)-1-[3-(6-methyl-pyridin-3-yloxy)-phenyl]ethylamine

https://huagongshe.com/reaction/2183459

반응식

참여 물질

역할이름HCID투입량
반응물Hydrochloric AcidHCID 313—
반응물(S)-{1-[3-(6-Methyl-pyridin-3-yloxy)-phenyl]-ethyl}-carbamic acid tert-butyl esterHCID 60004122—
용매MethanolHCID 887—
용매Diethyl EtherHCID 3283—
생성물(S)-1-[3-(6-methyl-pyridin-3-yloxy)-phenyl]ethylamineHCID 60004124141.6%

반응 단계

(S)-{1-[3-(6-Methyl-pyridin-3-yloxy)-phenyl]-ethyl}-carbamic acid tert-butyl ester (3.45 g, 10.52 mmol), hydrogen chloride in ether (36.8 mL, 1.0M) and methanol (5 mL) was stirred at room temperature for 6 h. The reaction mixture was concentrated in vacuo to provide the title compound (3.4 g, quantitative yield) as yellow solid.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06900210B2
출처 데이터셋uspto-grants-2005_05
ORD IDord-e63ac5ecff554945914a4d7b418d4464
출처 메모uspto-grants-2005_05