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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2183470Generated: November 2, 2026

3-(2-Fluorophenyl)prop-2-enoic acid → (S)-3-(2-fluoro-phenyl)-N-{1-[3-(pyrimidin-2-yloxy)-phenyl]-ethyl}-acrylamide

https://huagongshe.com/reaction/2183470

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Fluorophenyl)prop-2-enoic acidHCID 67977—
ReactantHCID 60004105HCID 60004105—
Product(S)-3-(2-fluoro-phenyl)-N-{1-[3-(pyrimidin-2-yloxy)-phenyl]-ethyl}-acrylamideHCID 69801962—

Reaction Steps

The title compound was prepared from 2-fluorocinnamic acid following the general procedures as described for Example 1 with the exception that (S)-1-[3-(pyrimidin-2-yloxy)-phenyl]-ethylamine was used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900210B2
Source datasetuspto-grants-2005_05
ORD IDord-63e168beb2784e2aaf7a84d6829b912d
Source noteuspto-grants-2005_05