反应详情

A mixture of 2,5-dimethyl-7-(2,4,6-trimethylphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-ol (1 mmol) in POCl3 (1.3 ml) was heated at reflux until all the starting material were consumed (about 1-3 hours). The mixture was concentrated to dryness. The residue was porued into ice-water and extracted with ethyl acetate. The organic layer was dried and concentrated to dryness to give the title compound.

1. temperaturewas heated
2. temperatureat reflux until all the starting material
3. customwere consumed (about 1-3 hours)
4. concentrationThe mixture was concentrated to dryness
5. extractionextracted with ethyl acetate
6. customThe organic layer was dried
7. concentrationconcentrated to dryness