Ethanol → HCID 10156218, compound

Participants

Reaction Steps

A mixture of 2-bromo-1-(4-chlorobenzo[b]thiophen-2-yl]ethan-1-one (0.42 g), 2-imidazolidinethione (0.11 g) and ethanol (9 ml) was heated under reflux for 20 minutes. Acetic acid (4 ml) was added and the mixture was heated under reflux for 17 hours then cooled in ice-water. The resulting solid was collected by filtration and dried in vacuo at 60° C. to give 3-(4-chlorobenzo[b]thiophen-2-yl)-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide (0.37 g) as a white solid, m.p. 273-274° C.

Provenance & Evidence