Ethanol → HCID 22473835, compound

Participants

Reaction Steps

A mixture of 2-bromo-1-(7-chlorobenzo[b]thiophen-2-yl)propan-1-one (2.32 g), 2-imidazolidinethione (0.53 g), ethanol (25 ml) and acetic acid (12.5 ml) was heated under reflux for 3 hours and allowed to cool to ambient temperature. The resulting solid was collected by filtration, washed with ethanol and dried in vacuo to give 3-(7-chlorobenzo[b]thiophen-2-yl)-2-methyl-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide (1.12 g) as a white solid, m.p. 294-295° C.

Provenance & Evidence