4-Chloro-2,5-difluorobenzonitrile → HCID 91612117, compound

HRID 2183852Notes

Reaction equation

HRID 2183852 reaction equation
[CH3:1][N:2]([CH2:10][CH2:11][CH:12]([OH:17])[C:13]([F:16])([F:15])[F:14])[C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6].[Cl:18][C:19]1[C:26]([F:27])=[CH:25][C:22]([C:23]#[N:24])=[C:21](F)[CH:20]=1>CN(C)C=O>[Cl:18][C:19]1[C:26]([F:27])=[CH:25][C:22]([C:23]#[N:24])=[C:21]([CH:20]=1)[O:17][CH:12]([C:13]([F:14])([F:15])[F:16])[CH2:11][CH2:10][N:2]([CH3:1])[C:3](=[O:9])[O:4][C:5]([CH3:8])([CH3:6])[CH3:7]

Participants

4

Reactant 2

HCID 112753024-Chloro-2,5-difluorobenzonitrileHCID 21928363tert-butyl N-methyl-N-(4,4,4trifluoro-3-hydroxybutyl)carbamate

Product 1

HCID 91612117HCID 91612117, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The subtitle compound was prepared according to the method of Example 3 step (b) using methyl-(4,4,4-trifluoro-3-hydroxybutyl)carbamic acid, 1,1-dimethylethyl ester and 4-chloro-2,5-difluorobenzonitrile in N,N-dimethylformamide.

Sources & evidence

ORD record
ord-2be81bcc9bf14519b9ce39989566fac8
Source dataset
uspto-grants-2005_05
Patent number
US06900243B2

Reaction notes

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