4-Chloro-2,5-difluorobenzonitrile → HCID 91351656, compound

HRID 2183853Notes

Reaction equation

HRID 2183853 reaction equation
[OH:1][CH:2]([CH:14]=[CH2:15])[CH2:3][CH2:4][N:5]([CH3:13])[C:6](=[O:12])[O:7][C:8]([CH3:11])([CH3:10])[CH3:9].[Cl:16][C:17]1[C:24]([F:25])=[CH:23][C:20]([C:21]#[N:22])=[C:19](F)[CH:18]=1>CN(C)C=O>[Cl:16][C:17]1[C:24]([F:25])=[CH:23][C:20]([C:21]#[N:22])=[C:19]([CH:18]=1)[O:1][CH:2]([CH:14]=[CH2:15])[CH2:3][CH2:4][N:5]([CH3:13])[C:6](=[O:12])[O:7][C:8]([CH3:11])([CH3:9])[CH3:10]

Participants

4

Reactant 2

HCID 112753024-Chloro-2,5-difluorobenzonitrileHCID 87977588HCID 87977588, compound

Product 1

HCID 91351656HCID 91351656, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The subtitle compound was prepared according to the method of Example 3 step (b) using (3-hydroxy-4-pentenyl)methylcarbamic acid, 1,1-dimethylethyl ester and 4-chloro-2,5-difluorobenzonitrile in N,N-dimethylformamide.

Sources & evidence

ORD record
ord-086671285d544014894c8516e1ed0ea9
Source dataset
uspto-grants-2005_05
Patent number
US06900243B2

Reaction notes

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