4-Chloro-2,5-difluorobenzonitrile → HCID 90947138, compound

HRID 2183854Notes

Reaction equation

HRID 2183854 reaction equation
[CH:1]1([CH:6]([OH:18])[CH2:7][CH2:8][N:9]([CH3:17])[C:10](=[O:16])[O:11][C:12]([CH3:15])([CH3:14])[CH3:13])[CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:19][C:20]1[C:27]([F:28])=[CH:26][C:23]([C:24]#[N:25])=[C:22](F)[CH:21]=1>CN(C)C=O>[Cl:19][C:20]1[C:27]([F:28])=[CH:26][C:23]([C:24]#[N:25])=[C:22]([CH:21]=1)[O:18][CH:6]([CH:1]1[CH2:2][CH2:3][CH2:4][CH2:5]1)[CH2:7][CH2:8][N:9]([CH3:17])[C:10](=[O:16])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15]

Participants

4

Reactant 2

HCID 112753024-Chloro-2,5-difluorobenzonitrileHCID 91134452HCID 91134452, compound

Product 1

HCID 90947138HCID 90947138, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The subtitle compound was prepared according to the method of Example 3 step (b) using (3-cyclopentyl-3-hydroxypropyl)methylcarbamic acid, 1,1-dimethylethyl ester and 4-chloro-2,5-difluorobenzonitrile in N,N-dimethylformamide.

Sources & evidence

ORD record
ord-de56710f228f4ffd9ebb7e47aadcfbef
Source dataset
uspto-grants-2005_05
Patent number
US06900243B2

Reaction notes

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