Bis(2-amino-1H-imidazole) sulphate → HCID 69708146, compound

Participants

Reaction Steps

1-(2,2,4-Trimethyl-[1,3]dioxolan-4-yl)ethanone was converted to 3,3-diethoxy-1-(2,2,4-trimethyl-[1,3]dioxolan-4-yl)propan-1-one as described in Example 3 then condensed with 2-aminoimidazole sulfate as in Example 2 to give 7-(2,2,4-trimethyl-[1,3]dioxolan-4-yl)imidazo[1,2-α]pyrimidine as a pale orange solid (7.10 g, 96%): δH (360 MHz, d6-DMSO) 1.31 (3H, s), 1.47 (3H, s), 1.57 (3H, s), 4.05 (1H, d, J 9), 4.49 (1H, d, J 9), 7.27 (1H, d, J 7), 7.71 (1H, d, J 1), 7.92 (1H, d, J 1), 8.98 (1H, d, J 7).

Provenance & Evidence