Chlorosuccinimide → HCID 22475115, compound

HRID 2184143Notes

Reaction equation

HRID 2184143 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1([C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][C:23]=2[F:29])[O:13][C:12]2[CH:14]=[C:15]([F:21])[C:16]([S:18]([OH:20])=[O:19])=[CH:17][C:11]=2[O:10]1.[Cl:30]N1C(=O)CCC1=O>C(Cl)(Cl)Cl>[F:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[C:9]1([C:22]2[CH:27]=[CH:26][C:25]([F:28])=[CH:24][C:23]=2[F:29])[O:13][C:12]2[CH:14]=[C:15]([F:21])[C:16]([S:18]([Cl:30])(=[O:20])=[O:19])=[CH:17][C:11]=2[O:10]1

Participants

4

Reactant 2

HCID 31398ChlorosuccinimideHCID 22475230HCID 22475230, compound

Product 1

HCID 22475115HCID 22475115, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of 2,2-bis-(2,4-difluoro-phenyl)-6-fluoro-benzo[1,3]dioxole-5 sulfinic acid (3.2 g, 7 mmol) in chloroform (25 mL) was added N-chlorosuccinimide (1.0 g, 7 mmol, 1.0 eq.) at 20° C. After 40 min, the reaction mixture was filtered and the filtrate was evaporated. The residue was suspended in dichloromethane, dried over sodium sulfate and the solvent was removed in vacuo, affording the title product as a light yellow gum.

Workup

  1. filtrationthe reaction mixture was filtered
  2. customthe filtrate was evaporated
  3. dry with materialdried over sodium sulfate
  4. customthe solvent was removed in vacuo

Sources & evidence

ORD record
ord-2e03287616a74e7c924d68cbdf4375ef
Source dataset
uspto-grants-2005_05
Patent number
US06900227B2

Reaction notes

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