Triphenylphosphine → 5-(Aminomethyl)picolinonitrile

HRID 2184225Notes

Reaction equation

HRID 2184225 reaction equation
[C:1]([C:3]1[N:8]=[CH:7][C:6]([CH2:9][N:10]=[N+]=[N-])=[CH:5][CH:4]=1)#[N:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>O>[C:1]([C:3]1[N:8]=[CH:7][C:6]([CH2:9][NH2:10])=[CH:5][CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 219046275-(Azidomethyl)pyridine-2-carbonitrile

Product 1

HCID 113557155-(Aminomethyl)picolinonitrile

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The compound obtained in (a) was dissolved in 45 ml of TEF and 1.2 ml of water and, while stirring, 11.2 g of triphenylphosphine were added in portions. The reaction mixture was left to stand at RT overnight.

Workup

  1. waitThe reaction mixture was left

Sources & evidence

ORD record
ord-fc281da529f9451ca2864079c28cc7d5
Source dataset
uspto-grants-2005_05
Patent number
US06900319B2

Reaction notes

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