HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 22476088, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-(Bromomethyl)-3-methoxybenzonitrile | HCID 14752995 | — |
| Reactant | Phthalimide potassium salt | HCID 24194345 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22476088 | HCID 22476088 | 68.5% |
Reaction Steps
24.4 g (108 mol) of 4-bromomethyl-3-methoxybenzonitrile dissolved in 125 ml of DMF and 20.0 g of potassium phthalimide were stirred at RT for 24 h and then at 50° C. for 1 h. The mixture was poured into water, whereupon the product precipitated as solid. 21.5 g (68%) of the product were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06900319B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-b3cc4f5af08f4e3899e5bffc6d891be8 |
| Source note | uspto-grants-2005_05 |