HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine, 4-benzoyl-1-(1,2-dioxo-2-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-2-methyl-, (2R)- → Bms-488043
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine, 4-benzoyl-1-(1,2-dioxo-2-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-2-methyl-, (2R)- | HCID 5495793 | — |
| Reactant | Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate | HCID 22893810 | — |
| Product | Bms-488043 | HCID 507806 | — |
Reaction Steps
Compound 5ao, N-(benzoyl)-N′-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]-piperazine was prepared by the same method used to prepare compound 5a but the starting material was Potassium (4,7-dimethoxy-6-azaindole-3-yl)-oxoacetate. The compound was purified by silica gel chromatography using EtOAc as the eluting solvent to give a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06900323B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-67815cdc8a7744d480ba3c925fc1920d |
| Source note | uspto-grants-2005_05 |