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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184255Generated: October 25, 2026

Piperazine, 4-benzoyl-1-(1,2-dioxo-2-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-2-methyl-, (2R)- → Bms-488043

https://huagongshe.com/reaction/2184255

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazine, 4-benzoyl-1-(1,2-dioxo-2-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-2-methyl-, (2R)-HCID 5495793—
ReactantPotassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetateHCID 22893810—
ProductBms-488043HCID 507806—

Reaction Steps

Compound 5ao, N-(benzoyl)-N′-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]-piperazine was prepared by the same method used to prepare compound 5a but the starting material was Potassium (4,7-dimethoxy-6-azaindole-3-yl)-oxoacetate. The compound was purified by silica gel chromatography using EtOAc as the eluting solvent to give a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900323B2
Source datasetuspto-grants-2005_05
ORD IDord-67815cdc8a7744d480ba3c925fc1920d
Source noteuspto-grants-2005_05