HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 59075088, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 69547056 | HCID 69547056 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 59075088 | HCID 59075088 | 84.4% |
Reaction Steps
The ester (54 mg) was dissolved in methanol (3 mL) and treated with 5 M aqueous solution of sodium hydroxide (0.5 mL) and stirred at ambient temperature for 1 hour. 7-{(S)-2-[3-hydroxy-3-(5-o-tolyl-furan-2-yl)-propyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid (54) (71) (45 mg, 0.10 mmol) resulted upon treatment with 1 M aqueous hydrochloric acid and extraction with ethyl acetate: MS: 428 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06900336B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-06f862ec8a264e738456efb8269b0b4a |
| Source note | uspto-grants-2005_05 |