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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184336Generated: October 31, 2026

Hydrochloric Acid → HCID 59075088, compound

https://huagongshe.com/reaction/2184336

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthyl AcetateHCID 8857—
ReactantSodium HydroxideHCID 14798—
ReactantHCID 69547056HCID 69547056—
SolventMethanolHCID 887—
ProductHCID 59075088HCID 5907508884.4%

Reaction Steps

The ester (54 mg) was dissolved in methanol (3 mL) and treated with 5 M aqueous solution of sodium hydroxide (0.5 mL) and stirred at ambient temperature for 1 hour. 7-{(S)-2-[3-hydroxy-3-(5-o-tolyl-furan-2-yl)-propyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid (54) (71) (45 mg, 0.10 mmol) resulted upon treatment with 1 M aqueous hydrochloric acid and extraction with ethyl acetate: MS: 428 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900336B2
Source datasetuspto-grants-2005_05
ORD IDord-06f862ec8a264e738456efb8269b0b4a
Source noteuspto-grants-2005_05