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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184356Generated: October 31, 2026

Methylamine → 3-[4-(3-Fluoro-benzyloxy)-phenyl]-propynoic Acid Methylamide

https://huagongshe.com/reaction/2184356

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant3-{4-[(3-Fluorophenyl)methoxy]phenyl}prop-2-ynoic acidHCID 69291743—
Product3-[4-(3-Fluoro-benzyloxy)-phenyl]-propynoic Acid MethylamideHCID 1177856445%

Reaction Steps

The title compound is prepared in analogy to example 5 d), starting from [4-(3-fluoro-benzyloxy)-phenyl]-propynoic acid and aqueous methylamine. Colorless solid. Yield=45%. MS: m/e=284.1 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900354B2
Source datasetuspto-grants-2005_05
ORD IDord-fc015680870b44a9a3323d3b0a77f8cb
Source noteuspto-grants-2005_05