Ethylamine → HCID 69289483, compound

HRID 2184362Notes

Reaction equation

HRID 2184362 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][CH:20]=1)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]=[CH:14][C:15](Cl)=[O:16])=[CH:9][CH:8]=1.[CH2:21]([NH2:23])[CH3:22]>ClCCl>[CH2:21]([NH:23][C:15](=[O:16])[CH:14]=[CH:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]2[CH:18]=[CH:19][CH:20]=[C:2]([F:1])[CH:3]=2)=[CH:8][CH:9]=1)[CH3:22]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 713776793-{4-[(3-Fluorophenyl)methoxy]phenyl}prop-2-enoyl chloride

Product 1

HCID 69289483HCID 69289483, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The title compound is prepared in analogy to example 9, using crude 3-[4-(3-fluoro-benzyloxy)-phenyl]-acryloyl chloride and a 2 M solution of ethylamine in dichloromethane. Colorless solid. Yield=72%. MS: m/e=300.3 (M++H).

Sources & evidence

ORD record
ord-d5b74875d5c749fd88ee47c08b485d1b
Source dataset
uspto-grants-2005_05
Patent number
US06900354B2

Reaction notes

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