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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184366Generated: October 29, 2026

4-Fluorobenzyl bromide → 3-[4-[(4-fluorophenyl)methoxy]phenyl]prop-2-enoic Acid

https://huagongshe.com/reaction/2184366

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl bromideHCID 68021—
ReactantP-Coumaric AcidHCID 637542—
Product3-[4-[(4-fluorophenyl)methoxy]phenyl]prop-2-enoic AcidHCID 80538256%

Reaction Steps

The title compound is prepared in analogy to example 12 a) from p-cumaric acid and 4-fluorobenzyl bromide. Yield=56%. Colorless solid. MS: m/e=271.0 (M−H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900354B2
Source datasetuspto-grants-2005_05
ORD IDord-8f962224259842e4bd48ca21674d1624
Source noteuspto-grants-2005_05