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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184369Generated: October 30, 2026

p-Xylyl bromide → N-Methyl-3-{4-[(4-methylphenyl)methoxy]phenyl}prop-2-enamide

https://huagongshe.com/reaction/2184369

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Xylyl bromideHCID 7721—
Reactant3-(4-Hydroxyphenyl)-N-methylprop-2-enamideHCID 54400570—
ProductN-Methyl-3-{4-[(4-methylphenyl)methoxy]phenyl}prop-2-enamideHCID 6866889344%

Reaction Steps

The title compound is prepared in analogy to example 11 b) from 3-(4-hydroxy-phenyl)-N-methyl-acrylamide and 1-bromomethyl-4-methyl-benzene. Yield=44%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900354B2
Source datasetuspto-grants-2005_05
ORD IDord-cc31eda76e1444879e035fa48e2ca55c
Source noteuspto-grants-2005_05