Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184476Generated: October 29, 2026

Diethanolamine → 10-(Methoxycarbonyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid bis-(2-hydroxy-ethyl)-amide

https://huagongshe.com/reaction/2184476

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethanolamineHCID 8113—
Reactant10-(methoxycarbonyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acidHCID 21947773—
Product10-(Methoxycarbonyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid bis-(2-hydroxy-ethyl)-amideHCID 69796275—

Reaction Steps

The title compound was prepared by coupling the 10-(methoxycarbonyl)-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepine-3-carboxylic acid of step A with diethanolamine (1.2 equiv.), in the manner of Example 1, Step G,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900200B2
Source datasetuspto-grants-2005_05
ORD IDord-2ed68591c72c40b58b7064e1deee5eba
Source noteuspto-grants-2005_05