Hydrochloric Acid → HCID 21340317, compound

Participants

Reaction Steps

To 0.41 g of Compound 24 in 10 mL of DMF and 3 mL of pyridine at room temperature is added 0.57 g of α-FMOC-L-lysine hydrochloride. The mixture is stirred at room temperature for three days, followed by warming at 35° C. for 30 minutes. The solution is poured into 130 mL of cold 1 M HCl. The crude residue is filtered and dried in vacuo then purified on a silica gel column to yield 0.55 g of the α-FMOC-L-lysine 25.

Provenance & Evidence