Ethyl Acetate → HCID 22610274, compound

HRID 2184701Notes

Reaction equation

HRID 2184701 reaction equation
C(OC([C:6]1([CH:14]=[O:15])[S:13][C:12]2[CH:11]=[CH:10][NH:9][C:8]=2[CH2:7]1)=O)C.[O-]S([O-])(=O)=O.[Mg+2].[C:22]([O:25]CC)(=[O:24])C>>[CH:14]([C:6]1[S:13][C:12]2[CH:11]=[C:10]([C:22]([OH:25])=[O:24])[NH:9][C:8]=2[CH:7]=1)=[O:15]

Participants

4

Reactant 3

HCID 8857Ethyl AcetateHCID 24083Sulfuric acid magnesium salt (1:1)HCID 86758102HCID 86758102, compound

Product 1

HCID 22610274HCID 22610274, compound

Procedure

2-Formyl-4H-thieno[3,2-b]pyrrole-carboxylic acid ethyl ester (see, for example, Gale, W. W. et al., J. Org. Chem., 29: 2160-2165 (1964)) was hydrolyzed according to Procedure F (50° C. overnight; acidified aqueous phase extracted with ethyl acetate; combined organic phases dried over MgSO4, concentrated).

Sources & evidence

ORD record
ord-80b3711ada89488fa7f4985553941b94
Source dataset
uspto-grants-2002_06
Patent number
US06399601B1

Reaction notes

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