Sulfuric Acid → HCID 135706125, compound

Participants

Reaction Steps

10 g of 2-(4-cyanobenzyl)-6-(3,4-dihydroxyphenyl)-5-ethyl-2,3,4,5-tetrahydropyridazin-3-one are added with stirring to a cooled solution of 1.2 g of NaOH in 100 ml of water and the mixture is subsequently stirred for 10 hours. It is warmed cautiously and a stream of air is passed through the solution. Cooled sulfuric acid and water are then added. The mixture is worked up in the customary manner and 2-(4-carboxybenzyl)-6-(3,4-dihydroxyphenyl)-5-ethyl-2,3,4,5-tetrahydropyridazin-3-one is obtained.

Provenance & Evidence