反应详情

To a solution of 0.22 g of the compound of example 27 and 0.08 mL of triethylamine (TEA) in 5 mL of CH2Cl2, stirred at r.t. under anhydrous nitrogen atmosphere, was added dropwise a solution of 0.04 mL of methanesulphonyl chloride in 0.5 mL of CH2Cl2. The solution was stirred for 6 h at room temperature, afterwards, it was evaporated to dryness in vacuo and the residue was purified by flash chromatography (CH2Cl2-MeCN 9:1) affording 0.10 g (39%) of the title compound.

1. customafterwards, it was evaporated to dryness in vacuo
2. customthe residue was purified by flash chromatography (CH2Cl2-MeCN 9:1)